Olmesartan Medoxomil Intermediate CAS 144689-93-0 Purity >99.0% (HPLC) Factory

Chemical Name: Ethyl 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylate CAS: 144689-93-0 Purity: >99.0% (HPLC) Appearance: Pale Yellow to Off-White Powder Intermediate of Olmesartan Medoxomil   E-Mail: alvin@ruifuchem.com

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Chemical Properties:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moistureRuifu Chemical Supply Olmesartan Medoxomil Intermediates With High Quality: 4,5-Dimethyl-1,3-Dioxol-2-One (DMDO) CAS 37830-90-3 4-Chloromethyl-5-Methyl-1,3-Dioxol-2-One (DMDO-Cl) CAS 80841-78-7 Ethyl 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylate CAS 144689-93-0 Diethyl 2-Propyl-1H-Imidazole-4,5-Dicarboxylate CAS 144689-94-1 Trityl Olmesartan Ethyl Ester CAS 144690-33-5 Trityl Olmesartan Acid CAS 761404-85-7 N2-Trityl Olmesartan Acid CAS 752179-89-8 Trityl Olmesartan Medoxomil CAS 144690-92-6 Olmesartan Medoxomil CAS 144689-63-4
Item Specifications
Appearance Pale Yellow to Off-White Powder
Identification HPLC: The retention time of the major peak in the chromatogram of the sample corresponds to that of the standard as obtained in purity and related substances
Purity / Analysis Method >99.0% (HPLC)
Water (by Karl Fischer) <0.50%
Residue on Ignition <0.50%
Impurity A <1.00%
Impurity B <1.00%
Impurity C <0.50%
Impurity D <0.10%
Impurity E <0.10%
Impurity F <0.50%
Max. Unknown Impurity <0.50%
Unknown Total Impurities <1.00%
Total Impurities <1.00%
Test Standard Enterprise Standard
Usage Intermediate of Olmesartan Medoxomil (CAS: 144689-63-4)

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Chemical Name Ethyl 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylate
Synonyms 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-1H-Imidazole-5-Carboxylic Acid Ethyl Ester; Ethyl 4-(2-Hydroxypropan-2-yl)-2-Propyl-1H-Imidazole-5-Carboxylate; Ethyl 4-(2-Hydroxy-2-Propyl)-2-Propyl-1H-Imidazole-5-Carboxylate
CAS Number 144689-93-0
CAT Number RF-PI1619
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C12H20N2O3
Molecular Weight 240.30
Melting Point 98.0~100.0℃
Density 1.131±0.06 g/cm3
Brand Ruifu Chemical

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Application:

Ethyl 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylate (CAS: 144689-93-0) is an intermediate of Olmesartan Medoxomil (CAS: 144689-63-4). Olmesartan Medoxomil was launched in the US as Benicar, an orally administered treatment for hypertension. Olmesartan Medoxomil is an angiotensin II receptor antagonist used to treat high blood pressure. Olmesartan works by blocking the binding of angiotensin II to the AT1 receptors in vascular muscle. By blocking the binding rather than the synthesis of angiotensin II, Olmesartan inhibits the negative regulatory feedback on renin secretion.

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