Chemical Properties:
Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool, dry (≤4℃) warehouse away from incompatible substances. Protect from light, heat and moisture. Store away from oxidizing agent.Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of N-Boc-3-Iodo-L-Alanine Methyl Ester (Boc-β-Iodo-Ala-OMe) (CAS: 93267-04-0) with high quality. Ruifu Chemical supplys a series of amino acids and derivatives. We can provide worldwide delivery, small and bulk quantities available. Purchase Boc-β-Iodo-Ala-OMe, Please contact: alvin@ruifuchem.com| Safety Statements | 24/25 - Avoid contact with skin and eyes. | F | 8 |
| WGK Germany | 3 | HS Code | 2922491990 |
Description:
Safety Information:
Package & Storage:
| Chemical Name | N-Boc-3-Iodo-L-Alanine Methyl Ester |
| Synonyms | Boc-β-Iodo-Ala-OMe; Boc-Ala(3-I)-OMe; Boc-Beta-Iodo-Ala-OMe; (R)-Boc-β-Iodo-Ala-Ome; N-(tert-Butoxycarbonyl)-3-Iodo-L-Alanine Methyl Ester; L-N-Boc-3-Iodoalanine Methyl Ester |
| Stock Status | In Stock |
| CAS Number | 93267-04-0 |
| Molecular Formula | C9H16INO4 |
| Molecular Weight | 329.13 g/mol |
| Melting Point | 45.0~55.0℃ (lit.) |
| Density | 1.551±0.06 g/cm3 |
| Sensitive | Light Sensitive, Heat Sensitive |
| Solubility | Soluble in Methanol |
| Storage Temp. | Cool & Dry Place (≤4℃) |
| COA & MSDS | Available |
| Category | Boc-Amino Acids |
| Brand | Ruifu Chemical |
Advantages:
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals. Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc. Advantages? Superior quality, affordable price, professional services and technical support, fast delivery. Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc. Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers. Factory Audit? Factory audit welcome. Please make an appointment in advance. MOQ? No MOQ. Small order is acceptable. Delivery Time? If within stock, three days delivery guaranteed. Transportation? By Express (FedEx, DHL), by Air, by Sea. Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided. Custom Synthesis? Can provide custom synthesis services to best fit your research needs. Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.FAQ:
Stable Supply: Maintain reasonable stock
Professional Service: One stop purchasing service
Technical Support: Technology solution available
Custom Synthesis Service: Ranged from grams to kilos
Fast Delivery: If within stock, three days delivery guaranteed
High Quality: Established a complete quality assurance system
Sufficient Capacity: Sufficient facilities and technicians
OEM Package: Custom package and label available
Specifications:
| Items | Inspection Standards | Results |
| Appearance | White to Light Yellow Crystals | Complies |
| Melting Point | 45.0~55.0℃ | 47.6~48.6℃ |
| Specific Rotation [α]20/D | -4.0° ± 1.0° (C=2 in MeOH) | -4.4° |
| Clarity of Solution | 0.3 gram in 2ml MeOH Clear Solution | Complies |
| Water Content (K.F.) | <1.00% | 0.18% |
| Purity / Analysis Method | >99.0% (HPLC) | 99.47% |
| IR Spectrum | In Accordance With the Standard | Complies |
| NMR Spectrum | In Accordance With the Standard | Complies |
| Conclusion | This Product by Inspection Accords with the Enterprise Standard | |
| Main Uses | Boc-Amino Acids; Peptide Synthesis; Pharmaceutical Intermediates | |
Application:
N-Boc-3-Iodo-L-Alanine Methyl Ester (Boc-β-Iodo-Ala-OMe) (CAS: 93267-04-0), Boc-amino acids, peptide synthesis, organic synthesis intermediate, pharmaceutical intermediates, biochemical reagents. Boc-β-Iodo-Ala-OMe is an organic intermediate, which can be obtained by reacting with elemental iodine Boc-L-serine methyl ester as raw material. Boc-L-serine methyl ester (20g,91mmol) is dissolved in THF(400mL) and cooled in an ice water bath. Triphenylphosphine (36g,137mmol) and pyridine (14g,177mmol) were added to the upper solution in turn, and then I2(34g,134mmol) was added in batches to maintain the temperature below 20 ℃ for 4 hours. After the reaction is completed, add ice water to the reaction solution to quench the reaction and extract it with ether. The organic phase obtained was washed with 1% hydrochloric acid, 5% Na2SO3 solution and saturated NaCl solution, dried with anhydrous Na2SO4, and concentrated after filtration. The resulting residue is added to petroleum ether, stirred to precipitate solids, filtered, and the filter residue is washed with petroleum ether. The filtrate was concentrated to get 26g of white or yellowish solid with 87% yield.