Chemical Properties:
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement. Storage Condition: Moisture sensitive. Store in sealed containers at cool and dry (2~8℃) warehouse away from incompatible substances. Protect from light and moisture. Incompatible with strong oxidizing agents and acids. Shipping: Deliver to worldwide by FedEx / DHL Express. Provide fast and reliable delivery. Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Bis(4-Nitrophenyl) Carbonate (NPC) (CAS: 5070-13-3) with high quality. Ruifu Chemical supplys a series of protecting reagents and coupling reagents. Ruifu can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase NPC, Please contact: alvin@ruifuchem.comDescription:
Package/Storage/Shipping:
| Chemical Name | Bis(4-Nitrophenyl) Carbonate |
| Synonyms | NPC; Bis(p-Nitrophenyl) Carbonate; Carbonic Acid Bis(4-Nitrophenyl) Ester; 4-Nitrophenyl Carbonate; 4,4'-Dinitrodiphenyl Carbonate; Di-4-Nitrophenyl Carbonate; Di-p-Nitrophenyl Carbonate; p,p'-Dinitrodiphenylcarbonate; |
| Stock Status | In Stock, Mass Production |
| CAS Number | 5070-13-3 |
| Molecular Formula | C13H8N2O7 |
| Molecular Weight | 304.21 g/mol |
| Melting Point | 137.0~144.0℃ |
| Density | 1.501±0.06 g/cm3 |
| Sensitive | Moisture Sensitive |
| Water Solubility | Insoluble in Water |
| Solubility | Soluble in Chloroform and Tetrahydrofuran |
| Storage Temp. | Cool & Dry Place (2~8℃) |
| COA & MSDS | Available |
| Category | Coupling Reagents |
| Brand | Ruifu Chemical |
Advantages:
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals. Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc. Advantages? Superior quality, affordable price, professional services and technical support, fast delivery. Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc. Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers. Factory Audit? Factory audit welcome. Please make an appointment in advance. MOQ? No MOQ. Small order is acceptable. Delivery Time? If within stock, three days delivery guaranteed. Transportation? By Express (FedEx, DHL), by Air, by Sea. Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided. Custom Synthesis? Can provide custom synthesis services to best fit your research needs. Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.FAQ:
Stable Supply: Maintain reasonable stock
Professional Service: One stop purchasing service
Technical Support: Technology solution available
Custom Synthesis Service: Ranged from grams to kilos
Fast Delivery: If within stock, three days delivery guaranteed
High Quality: Established a complete quality assurance system
Sufficient Capacity: Sufficient facilities and technicians
OEM Package: Custom package and label available
Specifications:
| Items | Inspection Standards | Results |
| Appearance | Off-White to Light Yellow Crystalline Powder | Complies |
| Melting Point | 137.0~144.0℃ | 139.7~140.9℃ |
| Loss on Drying | <0.50% | 0.11% |
| Residue on Ignition | <0.20% | <0.10% |
| Purity / Analysis Method | >99.0% (HPLC) | 99.76% |
| 300MHz | Consistent with Structure | Complies |
| Conclusion | The product has been tested & complies with the given specifications | |
5070-13-3 - Risk and Safety:
Application:
Hazard Symbols Xi - Irritant Risk Codes 36/38 - Irritating to eyes and skin. Safety Description S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. WGK Germany 3 FLUKA BRAND F CODES 10-21 HS Code 2920909090Bis(4-Nitrophenyl) Carbonate (NPC) (CAS: 5070-13-3), is used as a reagent for preparation of symmetrical and unsymmetrical urea and 4-nitrophenyl esters of N-protected amino acids. It acts as a peptide coupling reagent. It finds application as a reagent for the preparation of carbamate linked cytosines. NPC can be used as an intermediate for APIs such as Ritonavir (CAS: 155213-67-5), Rivastigmine (CAS: 123441-03-2) and Cobicistat (CAS: 1004316-88-4). Used as an organic synthesis intermediate, pharmaceutical intermediate, or chemical reagent.5070-13-3 ROS of NPC:
5070-13-3 Method of Analysis:
1. Properties: This product should be off-white to light yellow crystalline powder. 2. Content determination: octadecyl silane bonded silica gel as filler (250*4.6mm*5.0μm); Acetonitrile:Water =70:30 is the mobile phase; The detection wavelength was 254nm. Flow rate: 0.6ml/min; Theory board number press against NPC The main peak should be no less than 2000. Determination method: Take this product, make acetonitrile solution containing NPC 20μg in every 1ml, as the test product solution. 20μL of the test solution was injected into the chromatograph, and the retention time of the chromatogram to the main peak was 2 times. Results: Calculated by area normalization method, the NPC contained no less than 99.0%. 3. Melting point: The melting point of the product shall be determined according to the melting point determination method (Appendix VII C, 2010 Edition of Chinese Pharmacopoeia): 137.0~144.0 ℃. 4. NMR characterization: The frequency was 300MHz, and CDCl3 was used as solvent to conduct NMR characterization of samples at room temperature. 5. Loss on drying : Take this product at 60℃ vacuum drying to constant weight, weight loss shall not exceed 0.5%. 6. Storage: Store in a cool and dry place away from light (RT). 7. Reinspection period: one year.