Chemical Properties:
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.Manufacturer Supply, High Purity, Commercial Production Chemical Name: 6-Mercaptopurine CAS: 50-44-2| Item | Specifications |
| Appearance | Yellow Crystalline Powder |
| Assay | 97.0~102.0% |
| Melting Point | ≥300℃ |
| Organic Volatile Impurities | Meet the Requirement |
| Loss on Drying | ≤11.0% |
| Residue on Ignition | ≤0.20% |
| Hypoxanthine | ≤1.0% |
| Heavy Metals | ≤10ppm |
| Test Standard | United States Pharmacopoeia (USP) |
| Usage | API; Pharmaceutical Intermediates |
Description:
Specifications:
Package & Storage:
| Chemical Name | 6-Mercaptopurine |
| Synonyms | Mercaptopurine; 6-MP; 6-Mercaptopurine (monohydrate) |
| CAS Number | 50-44-2 |
| CAT Number | RF-PI487 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C5H4N4S |
| Molecular Weight | 152.18 |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
6-Mercaptopurine (CAS: 50-44-2) is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA. 6-Mercaptopurine is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive drug. Mercaptopurine inhibits purine nucleotide synthesis and metabolism by inhibiting an enzyme called Phosphoribosyl pyrophosphate amidotransferase (PRPP Amidotransferase). Mercaptopurine interferes with nucleotide interconversion and glycoprotein synthesis. Mercaptopurine, sold under the brand name Purinethol, specifically it is used to treat acute lymphocytic leukemia (ALL), chronic myeloid leukemia (CML), Crohn's disease, and ulcerative colitis.
