6-Iodo-4-Hydroxyquinazoline CAS 16064-08-7 Purity >98.5% (HPLC) Factory

Chemical Name: 6-Iodo-4-Hydroxyquinazoline Synonyms: 6-Iodoquinazolin-4-one  CAS: 16064-08-7 Purity: >98.5% (HPLC) Appearance: Pale Yellow to Brown Crystal Powder Intermediate of API (CAS: 388082-78-8)  E-Mail: alvin@ruifuchem.com

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Chemical Properties:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moistureManufacturer Supply Related Intermediates: Sodium Methanesulfinate CAS 20277-69-4 2-Aminoethyl Methyl Sulfone Hydrochloride CAS 104458-24-4 6-Iodo-4-Hydroxyquinazoline CAS 16064-08-7 5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde CAS 231278-84-5 CAS 231277-92-2 CAS 388082-77-7
Item Specifications
Appearance Pale Yellow to Brown Crystal Powder
Identification H-NMR, MS
Loss on Drying <1.00%
Residue on Ignition ≤0.20%
Purity / Analysis Method >98.5% (HPLC)
1 H NMR Spectrum Consistent With Structure
Test Standard Enterprise Standard
Usage Intermediate of API (CAS: 388082-78-8)

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Chemical Name 6-Iodo-4-Hydroxyquinazoline 
Synonyms 6-Iodoquinazolin-4-one; 6-Iodo-4-Quinazolinone; 6-Iodoquinazolin-4(3H)-one; 6-Iodo-4(1H)-Quinazolinone; 6-Iodo-4-Quinazolinol
CAS Number 16064-08-7
CAT Number RF-PI1627
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C8H5IN2O
Molecular Weight 272.04
Melting Point 271℃ (lit.)
Density   2.11±0.10 g/cm3
Brand Ruifu Chemical

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Application:

6-Iodo-4-Hydroxyquinazoline (CAS: 16064-08-7) is an intermediate in the synthesis of API (CAS: 388082-78-8). (CAS: 388082-78-8) is available in 250-mg tablets for oral administrationand is used in combination with Cabecitabine in thetreatment of breast cancer for those patients that over expressthe type 2 EGF-R and who have previously receivedtaxane, anthracycline, and trastuzumab therapy. The type 2EGF-R is one subtype of this receptor and is also known asHER2 or ErbB-2. The agent is a receptor TK inhibitor targetingthe ErbB-1 and ErbB-2 subtypes.

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