Chemical Properties:
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement. Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture. Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. Commercial Supply (CAS: 177036-94-1) Related Intermediates: CAS: 177036-94-1 Methyl 2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoate CAS: 178306-47-3 2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoic Acid CAS: 178306-51-9 (S)-2-Hydroxy-3-Methoxy-3,3-Diphenylpropionic Acid CAS: 178306-52-0 L-Proline Methyl Ester Hydrochlorid CAS: 2133-40-6 4,6-Dimethyl-2-(Methylsulfonyl)pyrimidine CAS: 35144-22-0| Item | Specifications | Specifications |
| Appearance | Yellow Crystalline Powder | Yellow Crystalline Powder |
| Purity / Analysis Method | ≥99.0% (HPLC) | 99.60% |
| Melting Point | 80.0~84.0℃ | 80.0~82.0℃ |
| Moisture (K.F) | ≤0.50% | 0.33% |
| Residue on Ignition | ≤0.30% | 0.09% |
| Single Impurity | ≤0.50% | <0.50% |
| Heavy Metals | ≤20ppm | <20ppm |
| 1 H NMR Spectrum | Consistent with Structure | Complies |
| Conclusion | The product has been tested and complies with the given specifications | |
| Main Use | Intermediate of API (CAS: 177036-94-1) | |
Description:
Specifications:
Package & Storage:
| Chemical Name | 4,6-Dimethyl-2-(Methylsulfonyl)pyrimidine |
| Abbreviation | DLMSP |
| CAS Number | 35144-22-0 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C7H10N2O2S |
| Molecular Weight | 186.23 |
| Melting Point | 80.0~84.0℃ |
| Density | 1.239g/cm3 |
| Solubility (Soluble in) | Methanol |
| COA & MSDS | Available |
| Sample | Available |
| Origin | Shanghai, China |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
35144-22-0 - Risk and Safety:
Hazard Symbols Xi - Irritant Risk Codes 36/37/38 - Irritating to eyes, respiratory system and skin. Safety Description S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
35144-22-0 - Application:
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 4,6-Dimethyl-2-(Methylsulfonyl)pyrimidine (CAS: 35144-22-0) with high quality. It's a pharmaceutical Intermediate can be used in the synthesis of API (CAS: 177036-94-1). (CAS: 177036-94-1) is a selective endothelin-A (ETA) receptor antagonist introduced for the oral treatment of patients with pulmonary arterial hypertension (PAH), to improve exercise capacity and delay clinical worsening. It is the third ET-receptor antagonist to be marketed for this indication behind bosentan and sitaxsentan. PAH is a rare disease of the small pulmonary arteries characterized by vascular proliferation and remodeling, resulting in a progressive increase in pulmonary vascular resistance and pulmonary arterial pressure, and ultimately, right ventricular failure and premature death. Early symptoms of PAH include gradual onset of shortness of breath, fatigue, palpitation, edema, and fainting.