Chemical Properties:
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.Manufacturer Commercial Supply Remdesivir and Related Intermediates with High Quality Remdesivir CAS 1809249-37-3 2-Ethyl-1-butanol CAS 97-95-0 Trimethylsilyl Cyanide CAS 7677-24-9 4-Nitrophenol CAS 100-02-7 2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate CAS 1911578-98-7 N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester CAS 1354823-36-1 (S)-2-Ethylbutyl 2-Aminopropanoate Hydrochloride CAS 946511-97-3 Remdesivir Metabolite (GS-441524) CAS 1191237-69-0 Remdesivir N-2 Intermediate CAS 1191237-80-5 2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5 7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine CAS 937046-98-5 Pyrrolo[1,2-F][1,2,4]Triazin-4-Amine CAS 159326-68-8 4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine CAS 1770840-43-1| Item | Specifications |
| Appearance | Yellowish or White Solid |
| Solubility | Soluble in CH2Cl2 and Insoluble in H2O |
| NMR and MS | Should Comply |
| Identification | IR and TLC |
| Moisture | ≤1.0% |
| Residue on Ignition | ≤0.50% |
| Any Individual Impurity | ≤0.50% |
| Heavy Metals | ≤50ppm |
| HPLC (210nm) | ≥99.0% |
| HPLC (ELSD) | ≥99.0% |
| Test Standard | Enterprise Standard |
| Usage | Intermediate of Remdesivir (CAS 1809249-37-3) |
Description:
Specifications:
Package & Storage:
| Chemical Name | 2,3,5-Tri-O-benzyl-D-ribonolactone |
| Synonyms | 2,3,5-Tri-O-Benzyl-D-Ribono-1,4-Lactone; Remdesivir Intermediate |
| CAS Number | 55094-52-5 |
| CAT Number | RF-PI301 |
| Stock Status | In Stock, Production Scale Up to Hundreds of Kilograms |
| Molecular Formula | C26H26O5 |
| Molecular Weight | 418.49 |
| Melting Point | 54.0-55.0℃ |
| Storage Condition | Room Temperature |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
2,3,5-Tri-O-benzyl-D-ribonolactone (CAS 55094-52-5) is a Remdesivir intermediate. Remdesivir (CAS 1809249-37-3) is a novel antiviral drug in the class of nucleotide analogs, used in treatment of COVID-19. Remdesivir (GS-5734) is a novel antiviral nucleoside analogue that inhibits murine hepatitis virus (MHV) with similar EC50 as SARS-CoV and MERS-CoV. Coronaviruses (CoVs) are positive-sense, single-stranded RNA viruses that infect a wide range of animal hosts. In humans, CoVs were recognized as typically causing colds and pneumonia until the emergence of severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002 and Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012 from zoonotic sources. Remdesivir is the monophosphoramidate prodrug of the C-adenosine nucleoside analogue GS-441524. In delayed brain tumor (DBT) cells infected with MHV, GS-5734 inhibited MHV more potently than GS-441524, with a GS-5734 EC50 of 0.03 M. Furthermore, EC50 values were determined after treatment with GS-441524 and GS-5734 in SARS-CoV- and MERS-CoV-infected primary human airway epithelial cell (HAE) cultures.
