1-Bromo-2-Butyne CAS 3355-28-0 Purity ≥99.0% (GC) Linagliptin Intermediate Factory

Chemical Name: 1-Bromo-2-Butyne

Synonyms: 2-Butynyl Bromide

CAS: 3355-28-0

Purity: ≥99.0% (GC)

Appearance: Colorless to Slight Yellow Liquid 

High Quality, Commercial Production

E-Mail: alvin@ruifuchem.com

Products Details

Chemical Properties:

Package: Bottle, 25kg/Barrel or 220kg Plastic drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.Manufacturer Supply Linagliptin and Related Intermediates: Linagliptin CAS 668270-12-0 Linagliptin Parent Nucleus Intermediate CAS 853029-57-9 8-Bromo-3-Methylxanthine CAS 93703-24-3 8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine CAS 666816-98-4 2-(Chloromethyl)-4-Methylquinazoline CAS 109113-72-6 (R)-3-(Boc-Amino)piperidine CAS 309956-78-3 (R)-(-)-3-Aminopiperidine Dihydrochloride CAS 334618-23-4 1-Bromo-2-Butyne CAS 3355-28-0
Item Specifications
Appearance Colorless to Slight Yellow Liquid
Purity / Analysis Method ≥99.0% (GC)
Moisture (K.F) ≤0.20%
Residue on Ignition ≤0.10%
Single Impurity ≤0.30%
Total Impurities ≤1.0%
Remarks The color will get darker after exposed to air frequently
Store in low-temperature, dark, dry and nitrogen-protected place
Use it out as soon as possible after opening
Test Standard Enterprise Standard
Usage Pharmaceutical Intermediates

Description:

Specifications:

Package & Storage:

Chemical Name 1-Bromo-2-Butyne
Synonyms 2-Butynyl Bromide
CAS Number 3355-28-0
CAT Number RF-PI500
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C4H5Br
Molecular Weight 132.99
Boiling Point  40.0~41.0℃/20 mmHg (lit.)
Density 1.519 g/ml at 25℃ (lit.)
Refractive Index n20/D 1.508(lit.)
Brand Ruifu Chemical

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Application:

1-Bromo-2-Butyne (CAS: 3355-28-0) is widely used in organic synthesis, synthesis of pharmaceutical intermediates and Active Pharmaceutical Ingredient (API) synthesis. 1-Bromo-2-Butyne is a key intermediate in the synthesis of Linagliptin (CAS: 668270-12-0) for the treatment of adults with type 2 diabetes mellitus. 1-Bromo-2-Butyne is a chemical whic his exploited in the synthesis of axially chiral teranyl compounds, alkylation of L-tryptophan methyl ester, 4-butynyloxybenzene sulfonyl chloride and mono-propargylated diene derivative. In addition to this, it is also used in the synthesis of isopropylbut-2-ynylamine, allenylcyclobutanol derivatives, allyl-[4-(but-2-ynyloxy)phenyl]sulfane, allenylindium and axially chiral teranyl compounds.

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