Chemical Properties:
Package: Bottle, Aluminum foil bag, 25kg/Cardboard Drum, or according to customer's requirement Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moistureShanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 1,1-Cyclopropanedicarboxylic Acid (CAS: 598-10-7) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. If you are interested in this product, please send detailed information includes CAS number, product name, quantity to us. Please contact: alvin@ruifuchem.com| Item | Specifications |
| Appearance | White or Off-White Powder |
| Purity / Analysis Method | >98.0% (GC) |
| Purity / Analysis Method | >98.0% (Neutralization Titration) |
| Melting Point | 130.0~138.0℃ |
| Water (by Karl Fischer) | <0.50% |
| Total Impurities | <2.00% |
| 1 H NMR Spectrum | Consistent With Structure |
| Solubility in H2O | Very Faint Turbidity Pass |
| Test Standard | Enterprise Standard |
| Usage | Pharmaceutical Intermediates; Cabozantinib Impurity |
Description:
Specifications:
Package & Storage:
| Chemical Name | 1,1-Cyclopropanedicarboxylic Acid |
| Synonyms | Cyclopropane-1,1-Dicarboxylic Acid; 1,1-Cyclopropanedicarboxylate; 1,1-Cyclopropane-2,2,3,3-d4-Dicarboxylic Acid |
| CAS Number | 598-10-7 |
| CAT Number | RF2882 |
| Stock Status | In Stock, Production Capacity 20 Tons per Month |
| Molecular Formula | C5H6O4 |
| Molecular Weight | 130.10 |
| Melting Point | 130.0~138.0℃ |
| Solubility in Water | Soluble in Water, Very Faint Turbidity |
| Hazard Note | Irritant |
| Hazard Class | 8 |
| Packing Group | III |
| HS Code | 29172090 |
| Shelf Life | 2 Years |
| Brand | Ruifu Chemical |
Advantages:
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals. Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc. Advantages? Superior quality, affordable price, professional services and technical support, fast delivery. Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc. Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers. Factory Audit? Factory audit welcome. Please make an appointment in advance. MOQ? No MOQ. Small order is acceptable. Delivery Time? If within stock, three days delivery guaranteed. Transportation? By Express (FedEx, DHL), by Air, by Sea. Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided. Custom Synthesis? Can provide custom synthesis services to best fit your research needs. Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.FAQ:
Stable Supply: Maintain reasonable stock
Professional Service: One stop purchasing service
Technical Support: Technology solution available
Custom Synthesis Service: Ranged from grams to kilos
Fast Delivery: If within stock, three days delivery guaranteed
High Quality: Established a complete quality assurance system
Application:
1,1-Cyclopropanedicarboxylic Acid (CAS: 598-10-7) is a dicarboxylic acid. It is an intermediate or impurity of Cabozantinib (CAS: 849217-68-1). Cabozantinib is a kind of a novel type of molecular targeted drugs developed by the United States Exelixis biopharmaceutical company. On November 29, 2012, the US Food and Drug Administration (FDA) approved the use of cabozantinib for the treatment of unresectable malignant local advanced or metastatic medullary thyroid carcinoma. 1,1-Cyclopropanedicarboxylic Acid is also used in the preparation of intermediates of Montelukast and Ketorolac. It is used to prepare spiro-cyclopropyl metallocycles. 1,1-Cyclopropanedicarboxylic Acid was used in the preparation of new heterocyclic derivatives of cyclopropane dicarboxylic acid containing thiadiazole and 1,2,4-triazole moieties. It was also used to prepare spiro-cyclopropyl metallocycles. It can also be used as a building block for the synthesis of a series of cyclopropanecarboxamides, having antifungal activity.Sufficient Capacity: Sufficient facilities and technicians
OEM Package: Custom package and label available